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Psychiatria Danubina, Vol. 26 No. suppl 1, 2014.

Meeting abstract

A POSSIBLE ROLE OF GUT MICROBIOTA IN THE BEHAVORIAL CONTROL OF ALCOHOL-DEPENDENT SUBJECTS

Philippe de Timary ; Université catholique de Louvain, Department of Adult Psychiatry and Institute of Neuroscience and Louvain Drug Research Institute, Avenue Hippocrate 10, 1200 Brussels, Belgium
Sophie Leclercq ; Université catholique de Louvain, Department of Adult Psychiatry and Institute of Neuroscience and Louvain Drug Research Institute, Avenue Hippocrate 10, 1200 Brussels, Belgium
Patrice Cani ; Université catholique de Louvain, Department of Adult Psychiatry and Institute of Neuroscience and Louvain Drug Research Institute, Avenue Hippocrate 10, 1200 Brussels, Belgium
Sébastien Matamoros ; Université catholique de Louvain, Department of Adult Psychiatry and Institute of Neuroscience and Louvain Drug Research Institute, Avenue Hippocrate 10, 1200 Brussels, Belgium
Peter Stärkel ; Université catholique de Louvain, Department of Adult Psychiatry and Institute of Neuroscience and Louvain Drug Research Institute, Avenue Hippocrate 10, 1200 Brussels, Belgium
Frederik Bäckhed ; Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden
Valentina Tremaroli ; Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden
Kristin Verbeke ; LFoRCe, Leuven, Belgium
Nathalie Delzenne ; Université catholique de Louvain, Department of Adult Psychiatry and Institute of Neuroscience and Louvain Drug Research Institute, Avenue Hippocrate 10, 1200 Brussels, Belgium

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Abstract

These observations suggest that alterations at the level of the gut microbiota influence the gut
permeability and activate specific inflammation pathways that are related to psychological symptoms of alcoholdependence.
Altogether these observations are consistent with a role of inflammation as one mediator of a gut-brain
communication in AD patients.

Keywords

alcohol-dependence; gut microbiota; inflammation; intestinal permeability; alcohol-craving

Hrčak ID:

265744

URI

https://hrcak.srce.hr/265744

Publication date:

5.11.2014.

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