Original scientific paper
https://doi.org/10.2478/aiht-2021-72-3596
Characteristics of unintentional ingestion of oral nonsteroidal anti-inflammatory drugs and analgesics in preschool children
Željka Babić
orcid.org/0000-0002-5335-9522
; Institute for Medical Research and Occupational Health, Croatian Poison Control Centre, Zagreb, Croatia
Nikolina Benco Kordić
; Children’s Hospital Zagreb, Department for Paediatric Clinical Pharmacology and Toxicology, Zagreb, Croatia
Arnes Rešić
; 2 Children’s Hospital Zagreb, Department for Paediatric Clinical Pharmacology and Toxicology, Zagreb, Croatia, 3 University of Split, University Department of Health Studies, Split, Croatia
Rajka Turk
; Institute for Medical Research and Occupational Health, Croatian Poison Control Centre, Zagreb, Croatia
Abstract
We characterised accidental ingestion of non-steroidal anti-inflammatory drugs and non-opioid analgesics in children aged 0–5 years between 2009 and 2019 by analysing records of telephone consultations with the Croatian Poison Control Centre (CPCC) and cases treated at the Children’s Hospital Zagreb (CHZ). Among the total of 466 identified cases (411 from CPPCC records and 55 from CHS hospital records), the most frequently ingested drugs were ibuprofen (47 %), paracetamol (20 %), ketoprofen (15 %), and diclofenac (11 %). In 94 % of the cases unsupervised children ingested the drug left within their reach. The remaining 6 % were dosing errors by parents or caregivers and involved liquid formulations as a rule. Our findings can serve as real-life examples informing preventive measures.
Keywords
diclofenac; ibuprofen; ketoprofen; NSAIDs; overdose; paracetamol; poisoning; toddlers
Hrčak ID:
268079
URI
Publication date:
23.12.2021.
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