Case report

Scleromyxedema Without Monoclonal Gammopathy Treated with Intravenous Immunoglobulins

Mathilde Letzelter ; Angers University Hospital, Angers, France
Xavier Grimaux ; Angers University Hospital, Angers, France

Abstract

Scleromyxedema is a generalized cutaneous mucinosis that may
cause internal damage. This condition is frequently associated with monoclonal
gammopathy. However, its physiopathological implications remains
uncertain. The natural development of scleromyxedema is unpredictable and
may lead to potentially fatal complications. Although there is no standardized
treatment, intravenous immunoglobulins are considered the best method
for treating scleromyxedema. The effects of this method of treatment on this
condition are not well known, and it could be argued that intravenous immunoglobulins
interact with the monoclonal gammopathy. This paper describes
a case of scleromyxedema without associated monoclonal gammopathy that
was treated effectively using monthly courses of treatment with intravenous
immunoglobulins.

Keywords

scleromyxedema, monoclonal gammopathy, intravenous immunoglobulins

Hrčak ID:

274445

URI

https://hrcak.srce.hr/274445

Publication date:

17.3.2021.

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