Original scientific paper
Relationship between AB0 blood groups and colorectal cancer
Irena Mihić-Lasan
; Department of Transfusion Medicine, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Marija Skoko
; Department of Transfusion Medicine, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Jelena Culej
; Department of Transfusion Medicine, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Tiha Vučemilo
; Department of Transfusion Medicine, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Deana Šturm
; Department of Transfusion Medicine, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Abstract
The distribution of the AB0 blood group system (A, B, 0 or AB) and Rhesus type (Rh-positive or Rh negative Rh+ or Rh-) was studied retrospectively in 981 patients with colorectal cancer. The distribution of ABO and Rh blood groups among the observed patients was similar to the distribution among the normal population in Croatia. No specific relationship has been established between the blood group type and colorectal cancer. There were significant differences in the proportions of the various ABO blood groups in Rh-positive and Rh-negative patients (chi-square = 15.18; p = 0.0017), with the A/O ratio of 1.15 and 0.75 in Rh-positive and Rh-negative patients, respectively. Further analysis confirmed that these significant differences were due to the O Rh-negative blood group. No significant difference could be found in the ABO distributions with regard to tumor stage.
Keywords
ABO blood group; Rhesus type; colorectal cancer; tumor stage
Hrčak ID:
276096
URI
Publication date:
30.11.2011.
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