Original scientific paper
https://doi.org/10.3325/cmj.2021.62.137
Anterior quadratus lumborum block for ambulatory laparoscopic cholecystectomy: a randomized controlled trial
Jan Sverre Vamnes
; Department of Anesthesiology, Østfold Hospital Trust, Moss, Norway
Marie Sørenstua
; Department of Anesthesiology, Østfold Hospital Trust, Moss, Norway
Knut Inge Solbakk
; Department of Anesthesiology, Østfold Hospital Trust, Moss, Norway
Birgitte Sterud
; Department of Anesthesiology, Østfold Hospital Trust, Moss, Norway
Ann-Chatrin Leonardsen
; Department of Anesthesiology, Østfold Hospital Trust, Moss, Norway
Abstract
Aim To explore the effects of an anterior quadratus lumborum block (QLB) on opioid consumption, pain, nausea,
and vomiting (PONV) after ambulatory laparoscopic cholecystectomy.
Methods This randomized controlled study recruited 70
patients scheduled for ambulatory laparoscopic cholecystectomy from January 2018 to March 2019. The participants
were randomly allocated to one of the following groups:
1) anterior QLB (n=25) with preoperative ropivacaine 3.75
mg/mL, 20 mL bilaterally; 2) placebo QLB (n=22) with preoperative isotonic saline, 20 mL bilaterally; and 3) controls
(n=23) given only standard intravenous and oral analgesia. The primary endpoint was opioid analgesic consumption. The secondary endpoints were pain (numeric rating
scale 0-10) and PONV (scale 0-3, where 0=no PONV and
3=severe PONV). Assessments were made up to 48 hours
postoperatively.
Results The groups did not significantly differ in opioids
consumption and reported pain at 1, 2, 24, and 48 hours
postoperatively. PONV in the QLB group was lower than in
the placebo and control groups.
Conclusion Preoperative anterior QLB for laparoscopic
cholecystectomy did not affect postoperative opioid requirements and pain. However, anterior QLB may decrease
PONV
Keywords
Hrčak ID:
278055
URI
Publication date:
29.4.2021.
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