Original scientific paper
The Skin as a Mirror of Internal Disease: Comorbidities and Epidemiology of Acne Vulgaris and Adult Female Acne – A Cross-sectional Study and Current State of Knowledge
Katarzyna P. Kaleta
; Department of Dermatology, Jagiellonian University Medical College, Krakow, Poland
Anna Bogusławska
; Department of Dermatology, Jagiellonian University Medical College, Krakow, Poland
Athanasios J. Stefanis
; Department of Dermatology, Third Faculty of Medicine, Charles University, Prague, Czech Republic
Agata Kłosowicz
; Department of Dermatology, Jagiellonian University Medical College, Krakow, Poland
Natalia Juśko
; Department of Dermatology, Stefan Zeromski Krakow Municipal Hospital, Krakow, Poland
Monika Kapińska-Mrowiecka
; Department of Dermatology, Stefan Zeromski Krakow Municipal Hospital, Krakow, Poland
Elżbieta Broniatowska
; Andrzej Frycz Modrzewski Krakow University, Faculty of Medicine and Health Sciences, Krakow, Poland
Anna Wojas-Pelc
; Department of Dermatology, Jagiellonian University Medical College, Krakow, Poland
Abstract
Acne vulgaris is a common skin condition affecting an increasing
number of adults and might be a clue to identifying systemic
disease. Objective of this study is assessment of the demographic and
clinical characteristic, including comorbidities, of patients with acne with
a special focus on adult female acne (AFA). This cross-sectional study analyzed
the medical records of 354 patients with acne (323 outpatients and
31 hospitalized). Data concerning patient age, sex, lesions morphology
and distribution on body areas, duration of the disease, Body Mass Index,
and dermatologic and systemic comorbidities were collected. 61% of all
patients were female, 45.37% of women were classified as AFA. The median
age of patients with acne was 24 years and 32.5 years for AFA. The
face was the most commonly affected area; patients with AFA had lesions
on their back than less frequently non-AFA. Predominant eruptions were
pustules and papules. 38.7% of patients had concomitant systemic chronic
disease, 15.25% had an endocrinologic disorder, and 6.21% had thyroid
gland dysfunction. Women with AFA had endocrinologic disorders
more frequently (P=0.002), whereas cutaneous signs of hyperandrogenism
were observed less frequently than in the non-AFA group (P=0.034).
AFA possess distinct clinical features and it should raise suspicion towards
possible underlying endocrinologic disturbance.
Keywords
acne vulgaris, adult women, epidemiology, comorbidity, hormones
Hrčak ID:
281286
URI
Publication date:
16.9.2020.
Visits: 448 *