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Sinonasal tumors: paraganglioma, nasal polyps, frontal sinus mucocele; diagnosis, therapy, prognosis – a case report
Stjepan Grabovac
; Department of Otorhinolaryngology, General Hospital Bjelovar, Croatia
Drago Prgomet
; Otorhinolaryngology and Cervicofacial Surgery Clinic, Clinical Hospital Center Zagreb, Croatia
Jasna Begić
; Department of Pathology, General Hospital Bjelovar, Croatia
Abstract
Paragangliomas are rare tumors that for a long time grow without symptoms and originate from neuroendocrinecells of the autonomous nervous system. They are extremely rare both in the nasal cavity and in the sinuses, and there have been only 28 cases described so far. We have shown clinical manifestation, therapy and histopathological analysis in a female patient, whose main symptoms such as the obstruction and the swelling at the base of the nose were caused by polyps and a frontal sinus cyst, while the third tumor was found intrasurgically. The immunohistochemical tests (NSE, NF, S100, CK, EMA, chromogranine, GF) confirmed that the third tumor was the paraganglioma. We have not found any description of paraganglioma associated with nasal polyps and frontal sinus cyst in literature reports published anywhere the world. In the case study, the authors have confirmed, apart from the possibility of endoscopic sinus surgery for paraganglioma, the value of endoscopically controlled biopsy in the patient's regular observation.
Keywords
nasal paraganglioma; nasal polyps; endoscopic surgery
Hrčak ID:
281744
URI
Publication date:
20.12.2004.
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