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Professional paper

https://doi.org/10.57140/mj.52.3.5

Non-Hodgkin's lymphoma of the frontal sinus. Case report and literature review

Sandra Doko ; University hospital center "Sestre milosrdnice", University hospital for tumors, Division of head and neck surgery, Department of surgical oncology, Zagreb, Croatia
Iva Kelava ; University hospital center "Sestre milosrdnice", University hospital for tumors, Division of head and neck surgery, Department of otorhinolaryngology, Zagreb, Croatia
Ana Penezić ; University hospital center "Sestre milosrdnice", University hospital for tumors, Division of head and neck surgery, Department of otorhinolaryngology, Zagreb, Croatia
Marko Velimir Grgić ; University hospital center "Sestre milosrdnice", University hospital for tumors, Division of head and neck surgery, Department of otorhinolaryngology, Zagreb, Croatia; University of Zagreb, School of Medicine


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Abstract

Primary frontal sinus Non-Hodgkin's lymphoma (NHL) is an extremely rare condition with 20 cases
published in the existing literature to date. We describe a 64-year-old patient who presented with right
orbital pain, severe headache and diplopia. He was initially diagnosed with acute exacerbation of chronic
rhinosinusitis and responded well to antibiotic treatment, but his symptoms returned. The diagnosis of
frontal sinus NHL was made only after functional endoscopic frontal sinus surgery was performed in general
anaesthesia. A tumor mass, which was filling the entire right frontal sinus, was completely removed and sent
to histopathological examination. The patient was finally diagnosed with diffuse large B-cell lymphoma of
the frontal sinus and referred to the haematology department for tumor staging and chemotherapy. This case
emphasizes the importance of early clinical suspicion and diagnosis, which leads to early treatment and
better prognosis.

Keywords

frontal sinus; paranasal sinus; diffuse large B-cell lymphoma; non-Hodgkin's lymphoma

Hrčak ID:

287904

URI

https://hrcak.srce.hr/287904

Publication date:

21.12.2022.

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