Case report, case study
Acral Melanoma in an Elderly Patient with Congenital Ichthyosis Vulgaris
Nicoleta Neagu
; State Clinic of Dermatology, Mureş County Hospital, Târgu Mureş, Romania; Department of Dermatology, University of Medicine, Pharmacy, Science and Tech- nology ‘George Emil Palade’ of Târgu Mureş, Romania;
Ovidiu Simion Cotoi
; Department of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Science and Technlology, Târgu Mureş, Romania
Mihaela Cornelia Sincu
; Department of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Science and Technlology, Târgu Mureş, Romania
Andreea Cătălina Tincu
; Department of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Science and Technlology, Târgu Mureş, Romania
Constantin Dasanau
; Department of Oncology, Eisenhower Lucy Curci Cancer Center, Rancho Mirage, California, USA; University of California San Diego Health, San Diego, California, USA
Mircea Ambros
orcid.org/0000-0003-4138-1295
; State Clinic of Dermatology, Mureş County Hospital, Târgu Mureş, Romania; Department of Dermatology, University of Medicine, Pharmacy, Science and Tech- nology ‘George Emil Palade’ of Târgu Mureş, Romania;
Abstract
Ichthyoses are a heterogeneous group of skin disorders featuring erythro-
derma and generalized scaling. The relationship between ichthyosis and melanoma has
not been well-characterized. Herein we present a unique case of acral melanoma of the
palm developing in an elderly patient with congenital ichthyosis vulgaris. Biopsy revealed
a superficially spreading melanoma with ulceration. To the best of our knowledge, no
acral melanomas have been reported so far in patients with congenital ichthyosis. Nev-
ertheless, considering the potential for invasion and metastasis, patients with ichthyosis
vulgaris should undergo regular clinical and dermatoscopic screening for melanoma.
Keywords
acral melanoma; ichthyosis; dermatoscopy; screening; skin cancer
Hrčak ID:
299648
URI
Publication date:
14.9.2022.
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