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Meeting abstract

https://doi.org/10.26800/LV-145-supl2-CR33

Drug - drug interaction in a patient with epilepsy and newly diagnosed paroxysmal atrial fibroundulation

Klara Bardač ; School of Medicine, University of Zagreb, Zagreb, Croatia
Lucija Dafne Blažević
Lucija Nevena Barišić
Iveta Merćep


Full text: english pdf 281 Kb

page 63-63

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Abstract

Cytochrome P450 isoenzymes have a major role in the metabolism of xenobiotics. They are mostly found in hepatocytes and oxidize majority of drugs, thus shifting them into their inactive form. Some of them can influence cytochromes’ activity while getting oxidized, simultaneously inducing or inhibiting them. This way, drug activity can be altered and their benefit in the management of the disease limited.

Keywords

anticoagulants; carbamazepine; cytochromes; phenobarbital

Hrčak ID:

303548

URI

https://hrcak.srce.hr/303548

Publication date:

23.4.2023.

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