Acta clinica Croatica, Vol. 62. No. 1, 2023.
Original scientific paper
https://doi.org/10.20471/acc.2023.62.01.02
Comparison of C-Reactive Protein Levels in Serum and Peritoneal Fluid in Early Diagnosis of Anastomotic Leakage after Colorectal Surgery
Dubravka Mužina Mišić
; Department of Surgery, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Mario Zovak
; Department of Surgery, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Mario Kopljar
; Department of Surgery, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Slaven Čiček
; Department of Surgery, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Zdenko Bilić
; Department of Surgery, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Abstract
In colorectal surgery, anastomotic leakage is a serious complication, leading to
higher postoperative morbidity and mortality. The aim of this study was to evaluate the accuracy of serum
and intraperitoneal C-reactive protein (CRP) in early diagnostics of anastomotic leakage on the
first four postoperative days after colorectal surgery. From January to October 2019, fifty-nine patients
with colorectal carcinoma were operated on, with formation of primary anastomosis. Anastomotic
leakage was diagnosed in eight patients. Comparing the levels of serum and intraperitoneal CRP, our
study showed that serum CRP was a better predictor of anastomotic leakage. Serum CRP levels lower
than 121 mg/L on postoperative day 4 were predictive of good healing of anastomosis.
Keywords
Colorectal carcinoma; Colorectal surgery; Anastomotic leakage; C-reactive protein
Hrčak ID:
307133
URI
Publication date:
1.4.2023.
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