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Case report, case study

https://doi.org/10.21857/ygjwrcp78y

Repeated intravenous thrombolytic therapy with rt-PA alteplase in treatment of early recurrent ischemic stroke

Josip Sekovanić
Sara Drnasin
Mislav Budišić
Lidija Dežmalj Grbelja
Marijana Bosnar Purerić
Marina Roje Bedeković


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Abstract

The 2019 year guidelines (American Heart Association / American Stroke Association – AHA/ASA) do not recommend treating recurrent acute ischemic stroke with alteplase in patients who had previ- ous stroke in last 3 months (1,9). According to the European Stroke Organisation`s (ESO) guidelines (year 2021), there is no clear consensus. The risk of reocclusion occurs in 14-34% of patients in whom recanalisation with alteplase has been achieved (1). In this paper we present the case of our 70-year old patient with early stroke recurrence and repeated thrombolytic therapy 9 hours after the first dose of alteplase.

Keywords

repeated thrombolytic therapy; early recurrent ischemic stroke; intravenous thrombolysis; recombinant tissue plasminogen activator; rt-PA; alteplase

Hrčak ID:

308345

URI

https://hrcak.srce.hr/308345

Publication date:

25.6.2023.

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