Skip to the main content

Professional paper

CLASSIFICATION AND LABELLING OF PPPS BASED ON TOXICOLOGICAL STUDIES ON MAMMALS (AND ALTERNATIVE METHODS)

Zorica Vitić-Ferenc orcid id orcid.org/0009-0002-4253-1291 ; Hrvatska agencija za poljoprivredu i hranu, Centar za zaštitu bilja, Osijek *
Edgar Kralj orcid id orcid.org/0000-0003-1293-6378 ; Hrvatska agencija za poljoprivredu i hranu, Centar za zaštitu bilja, Osijek

* Corresponding author.


Full text: croatian pdf 307 Kb

page 522-527

downloads: 140

cite


Abstract

Toxicology is a scientific discipline dealing with detection, prevention and treatment of adverse health effects caused by exposure to chemicals. During the evaluation of plant protection products, the results of animal testing and calculation method or extrapolation of test results are used. The focus is on avoiding the in vivo testing and animal welfare. Toxicological studies are acute oral, dermal and inhalation toxicity, skin and eye irritation/corrosion and skin sensitisation. The final assessment is based on the assessment of the toxicological properties of the active substance and co-formulants, in line with the EFSA conclusions for active substances and safety data sheets. During authorisation, product authorisation and label of reference member state are also used. The classification and labelling process is based on the codes prescribed in the Regulation (EC) No 1272/2008 (Službeni list Europske unije, 2008.), which should be stated on the label during the placement on the market. It is also necessary to carry out the assessment of the relevance of metabolites of active substances in groundwater if they exceed the limit of 0.1 µg/L according to SANCO/221/2000-rev 11 (European Commission, 2021).

Keywords

Hrčak ID:

311295

URI

https://hrcak.srce.hr/311295

Publication date:

13.12.2023.

Article data in other languages: croatian

Visits: 715 *