Acta clinica Croatica, Vol. 62. No. 3, 2023.
Original scientific paper
https://doi.org/10.20471/acc.2023.62.03.13
Glucose and Sodium Levels as Disease Outcome Predictors in Critically Ill Patients
Željka Dragila
; Osijek University Hospital Center, Osijek, Croatia
Andrea Dorokazi
; Slavonija Polyclinic, Osijek, Croatia
Damir Mihić
; Intensive Care Unit, Department of Internal Medicine, Osijek University Hospital Center, Osijek, Croatia
Domagoj Loinjak
; Intensive Care Unit, Department of Internal Medicine, Osijek University Hospital Center, Osijek, Croatia
Miroslav Šram
; Division of Cardiology, Department of Internal Medicine, Osijek University Hospital Center, Osijek, Croatia
Tatjana Bačun
; Faculty of Medicine in Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Division of Endocrinology, Department of Internal Medicine, Osijek University Hospital Center, Osijek, Croatia
*
* Corresponding author.
Abstract
The main aim of this study was to examine the association of glucose and sodium
level with diagnosis and disease outcome of critically ill patients. Glucose and sodium concentrations
of 283 patients admitted in critical condition to the Intensive Care Unit of the Department of
Internal Medicine in a period from November 1, 2015 to February 28, 2017 were reviewed. The most
common diagnoses in critically ill patients were acute kidney injury (26.1%) and sepsis (including
septic shock, 22.3%). Significantly lower glucose concentration was observed in patients with acute
kidney injury (p=0.02), whereas patients in sepsis and septic shock had a significantly higher sodium
concentration (p=0.04). Higher glucose level was related to higher mortality rate (p=0.001).
On the other hand, sodium level was not significantly associated with survival. Higher mortality, as
well as higher glucose concentration were more common in patients older than 65 years (p<0.001).
Study results showed significantly lower glucose concentrations in patients with acute kidney injury,
whereas in patients older than 65, glucose concentration was significantly higher. Patients in sepsis
and septic shock had significantly higher sodium concentrations. Higher concentration of glucose
was connected with higher mortality in the elderly, whereas sodium concentration did not show
connection with mortality.
Keywords
Critical illness; Glucose; Intensive care unit; Sodium
Hrčak ID:
315078
URI
Publication date:
1.11.2023.
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