Review article
https://doi.org/10.26800/LV-146-supl1-10
Vaccine allergy – excuse for not vaccinating?
Ivana Jerković
orcid.org/0009-0008-6805-0019
*
Mirjana Turkalj
* Corresponding author.
Abstract
Vaccination is an important public health measure that helps reduce the spread of infectious diseases and protects individual and community health. Even if an allergic reaction can occur to almost every vaccine, they are rare in practice, and especially rare to the active components of the vaccine. Adverse reactions, which can be allergic and non-allergic, IgE and non-IgE mediated, occur more often to some vaccine components, such as egg proteins, gelatin, antibiotics, additives. The association of vaccine components with systemic allergic reactions is very rare, while local reactions are more common. Children suspected of having an allergic reaction after vaccination should be referred to an allergist for testing. Suspicion to vaccine allergy should not be an excuse for not vaccinating children. Those with negative skin tests to vaaccine components and an inconclusive history can be revaccinated, while children with a convincing history and a positive skin test for one of the components of the vaccine can be vaccinated with a replacement vaccine or using gradually increasing doses. In this review, we will present the types of adverse reactions that can occur after vaccination, the most common components of the vaccine that can be responsible for these reactions, and an approach to children with suspected allergic reactions to vaccines. A better understanding of allergic reactions to vaccine components can help break down prejudices and unnecessary fears about vaccination and improve vaccination rates.
Keywords
ALLERGY; VACCINATION; ANAPHYLAXIS; VACCINE COMPONENTS; VACCINE REACTION
Hrčak ID:
315822
URI
Publication date:
11.4.2024.
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