Review article
Chronic Inflammation in Patients with Solid Organ Transplant
Jerko Barbić
Full text: croatian pdf 135 Kb
page 173-181
downloads: 173
cite
APA 6th Edition
Barbić, J. (2023). Chronic Inflammation in Patients with Solid Organ Transplant. Medicus, 32 (2. Transplantacija), 173-173. Retrieved from https://hrcak.srce.hr/index.php/315850
MLA 8th Edition
Barbić, Jerko. "Chronic Inflammation in Patients with Solid Organ Transplant." Medicus, vol. 32, no. 2. Transplantacija, 2023, pp. 173-173. https://hrcak.srce.hr/index.php/315850. Accessed 1 Sep. 2024.
Chicago 17th Edition
Barbić, Jerko. "Chronic Inflammation in Patients with Solid Organ Transplant." Medicus 32, no. 2. Transplantacija (2023): 173-173. https://hrcak.srce.hr/index.php/315850
Harvard
Barbić, J. (2023). 'Chronic Inflammation in Patients with Solid Organ Transplant', Medicus, 32(2. Transplantacija), pp. 173-173. Available at: https://hrcak.srce.hr/index.php/315850 (Accessed 01 September 2024)
Vancouver
Barbić J. Chronic Inflammation in Patients with Solid Organ Transplant. Medicus [Internet]. 2023 [cited 2024 September 01];32(2. Transplantacija):173-173. Available from: https://hrcak.srce.hr/index.php/315850
IEEE
J. Barbić, "Chronic Inflammation in Patients with Solid Organ Transplant", Medicus, vol.32, no. 2. Transplantacija, pp. 173-173, 2023. [Online]. Available: https://hrcak.srce.hr/index.php/315850. [Accessed: 01 September 2024]
Full text: english pdf 135 Kb
page 173-173
downloads: 141
cite
APA 6th Edition
Barbić, J. (2023). Chronic Inflammation in Patients with Solid Organ Transplant. Medicus, 32 (2. Transplantacija), 173-173. Retrieved from https://hrcak.srce.hr/index.php/315850
MLA 8th Edition
Barbić, Jerko. "Chronic Inflammation in Patients with Solid Organ Transplant." Medicus, vol. 32, no. 2. Transplantacija, 2023, pp. 173-173. https://hrcak.srce.hr/index.php/315850. Accessed 1 Sep. 2024.
Chicago 17th Edition
Barbić, Jerko. "Chronic Inflammation in Patients with Solid Organ Transplant." Medicus 32, no. 2. Transplantacija (2023): 173-173. https://hrcak.srce.hr/index.php/315850
Harvard
Barbić, J. (2023). 'Chronic Inflammation in Patients with Solid Organ Transplant', Medicus, 32(2. Transplantacija), pp. 173-173. Available at: https://hrcak.srce.hr/index.php/315850 (Accessed 01 September 2024)
Vancouver
Barbić J. Chronic Inflammation in Patients with Solid Organ Transplant. Medicus [Internet]. 2023 [cited 2024 September 01];32(2. Transplantacija):173-173. Available from: https://hrcak.srce.hr/index.php/315850
IEEE
J. Barbić, "Chronic Inflammation in Patients with Solid Organ Transplant", Medicus, vol.32, no. 2. Transplantacija, pp. 173-173, 2023. [Online]. Available: https://hrcak.srce.hr/index.php/315850. [Accessed: 01 September 2024]
Abstract
SUMMARY Organ transplantation is the optimal therapy for end-stage kidney disease. There are numerous factors related to the donor that affect the outcome of a kidney transplantation. The differences between living and deceased kidney donors are very well known. The transplanted organ is exposed to different forms of damage at different stages of organ transplantation. In the early phase, brain death of the donor and ischemia of the transplanted organ stimulate the release of damage-associated molecular patterns (DAMP) that activate inflammation in the transplanted organ. In addition to local inflammation, inflammation can also be systemic. Local inflammation in the transplanted organ promotes the activity of acquired immunity and causes chronic rejection. Chronic inflammation and activated acquired immunity lead to chronic local inflammation that disrupts the healing process causing fibrosis and ultimately loss of function of the transplanted organ. Systemic chronic inflammation can be associated with insulin resistance, obesity, diabetes, arterial hypertension, which all together represent a risk factor for general and cardiovascular morbidity and mortality in transplant patients.
Keywords
inflammation; transplantation; cytokines; damage-associated molecular patterns
Hrčak ID:
315850
URI
https://hrcak.srce.hr/315850
Publication date:
9.4.2024.
Article data in other languages:
croatian
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