Case report, case study

https://doi.org/10.21860/medflum2024_316205

Inverted Papilloma of the Septum: a Case Report and Our Experience in the Treatment of Patients with Sinonasal Inverted Papilloma

Nina Čuš ; Klinički bolnički centar Rijeka, Zavod za audiologiju i fonijatriju, Rijeka, Hrvatska *
Katarina Radobuljac ; Klinički bolnički centar Rijeka, Zavod za audiologiju i fonijatriju, Rijeka, Hrvatska
Dubravko Manestar ; Klinički bolnički centar Rijeka, Klinika za otorinolaringologiju i kirurgiju glave i vrata, Rijeka, Hrvatska
Marko Velepič ; Klinički bolnički centar Rijeka, Klinika za otorinolaringologiju i kirurgiju glave i vrata, Rijeka, Hrvatska
Diana Maržić ; Klinički bolnički centar Rijeka, Zavod za audiologiju i fonijatriju, Rijeka, Hrvatska

* Corresponding author.

Abstract

Aim: We present a case of a female patient diagnosed with inverted papilloma of the nasal septum and retrospective analysis of previous experiences in the treatment of patients with sinonasal inverted papilloma. The patients were treated at the Clinic for Otolaryngology and Head and Neck Surgery in the Clinical Hospital Center Rijeka. Case report: A 30-year-old patient with difficulty in breathing through the nose and frequent epistaxis came for an otolaryngological examination in 2022. Nasal endoscopy revealed a perforation in the anterior regions of the septum. Diagnostic process included mucosal biopsy, imaging, and blood tests to screen for c-ANCA and p-ANCA autoantibodies, as well as an angiotensin-converting enzyme (ACE) test. Pathohistological analysis established the diagnosis of inverted papilloma and surgical treatment was performed. After this case we did a retrospective analysis and established that in the period from April 2014 to March 2022, 22 patients with sinonasal inverted papilloma were treated in the Clinic for Otorhinolaryngology and Head and Neck Surgery, Rijeka Clinical Hospital Center. Experiences with their treatment are also presented in this paper. Conclusion: Patients with sinonasal inverted papilloma are successfully treated in our institution. Differential diagnosis of this tumor should be considered in young patients with atypical disease presentation. Further research is needed in order to clarify etiology and predict the possibility of recurrence and / or malignant alteration of these tumors.

Keywords

endoscopy; nasal septum; papilloma, inverted; paranasal sinuses

Hrčak ID:

316205

URI

https://hrcak.srce.hr/316205

Publication date:

1.6.2024.

Article data in other languages: croatian

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