Review article
https://doi.org/10.26332/seemedj.v7i2.300
The Effectiveness of Bupropion in Cigarette Smoking Cessation - A Narrative Review
Matea Prenc
; Department of Diagnostic and Interventional Radiology, University Hospital Centre Sisters of Charity, Zagreb, Croatia
*
Frano Perić
; Department of Radiology, General Hospital Dubrovnik, Croatia
Irena Petričić
; Department of Psychiatry, Sahlgrenska University Hospital, Gothenburg, Sweden
Mirjana Flegarić Bradić
; Department of Diagnostic and Interventional Radiology, University Hospital Centre Sisters of Charity, Zagreb, Croatia
Robert Rončević
; Department of Diagnostic and Interventional Radiology, University Hospital Centre Osijek, Croatia
* Corresponding author.
Abstract
Smoking is still a large indirect cause of premature death worldwide. The first line of treatment for smoking cessation is nicotine replacement therapy (NRT). Bupropion, a drug primarily developed as an antidepressant, in some countries is the first drug licensed for smoking cessation that is not associated with nicotine. The drug acts mostly through its inhibition of dopamine reuptake in the neuronal synapses, but other effects of bupropion may also have a role in smoking cessation. There have been many clinical studies of bupropion that have shown impressive results in helping patients with smoking cessation. Because of its antidepressant role, it is useful in smoking cessation in patients with depression. Through the years bupropion has proven to be a potential cost-effective alternative to NRT.
Keywords
bupropion; nicotine replacement therapy; smoking cessation
Hrčak ID:
319419
URI
Publication date:
19.7.2024.
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