Original scientific paper
https://doi.org/10.3325/cmj.2024.65.313
Is there a relationship between attitudes of general practitioners/family doctors and attitudes of their patients regarding industry-sponsored clinical investigations? A cross-sectional survey in a convenience sample of doctors and patients across nine European countries
Maja Marković Zoya
; ICON d.o.o., Zagreb, Croatia
Ksenija Kranjčević
; Department of Family Medicine, Zagreb University School of Medicine, Zagreb, Croatia
Jasna Vučak
; Department of Family Medicine, Rijeka University School of Medicine, Rijeka, Croatia
Ljubin Sukriev
; Association of General Practice/Family Medicine South East Europe
Josep Vidal-Alaball
; Central Catalonia Research Support Unit, Jordi Gol i Gurina Foundation, Gerència Atenció Primària i a la Comunitat Catalunya Central, Catalan Health Institute, Sant Fruitós de Bages, Spain
Catarina Matos de Oliveira
; Center for Health Technology and Services Research (CINTESIS), Faculty of Medicine of the University of Porto, Porto, Portugal
Donata Kurpas
; Family Medicine Department, Health Sciences Faculty, Wroclaw, Poland
İlhami Ünlüoğlu
; Department of Family Medicine, Eskisehir Osmangazi University (ESOGU), Eskisehir, Turkey
Zaim Jatić
; Department of Family Medicine, Faculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina
Nevena Todorović
; Department of Family Medicine, Faculty of Medicine, University of Banja Luka, Banja Luka, Bosnia and Herzegovina
Darinka Punoševac
; Section of General Medicine, Serbian Medical Society, Belgrade, Serbia
Marta Tundzeva
; Center for Family Medicine, University of St. Cyril and Methodius, Skopje, Republic of North Macedonia
Milena Cojić
; Department of Familiy Medicine, University of Montenegro, Podgorica, Montenegro
M Mümtaz Maziociğlu
; Department of Family Medicine, Ericyes Faculty of Medicine University of Kayseri, Kayseri, Turkey
Vladimir Trkulja
orcid.org/0000-0002-0968-1194
; Department of Pharmacology, Zagreb University School of Medicine, Zagreb, Croatia
*
* Corresponding author.
Abstract
Aim To assess the relationship between the attitudes of general practitioners/family medicine doctors (GP/FD) and of their patients toward
industry-sponsored clinical research.
Methods A cross-sectional survey included volunteer GPs/FDs who
then enrolled and interviewed their patients. Data were analyzed in
hierarchical models (patients nested in GPs/FDs, nested in countries/
regions).
Results A total of 201 GPs/FDs from nine European countries responded to the invitation and enrolled 995 of their patients. We observed
mild associations between some of the GPs/FDs’ attitudes (general
opinion on sponsored clinical studies, appreciation of the general values of such studies, views about the importance of participant protection/privacy) and some of the patients’ attitudes (appreciation of the
general values and of risks associated with sponsored clinical studies,
importance assigned to potential personal benefits from participation). We observed no association between GPs/FDs’ attitudes and patients’ willingness to participate in such studies. However, willingness
to participate increased with higher patients’ appreciation of the general values of sponsored studies, decreased with higher patients’ appreciation of associated risks, and showed a quadratic trend across the
levels of importance assigned by patients to potential personal benefits (willingness was higher when the assigned importance was very
low or very high). More importance to GP/FD’s advice in this respect
was assigned by patients who assigned more importance to potential
personal benefits, who were better educated, and who resided in rural/suburban dwellings.
Conclusions In the present convenience sample, lay-person attitudes about and willingness to participate in industry-sponsored clinical studies were associated with the attitudes of their GPs/FDs
Keywords
Hrčak ID:
336460
URI
Publication date:
20.8.2024.
Visits: 31 *