Meeting abstract
Histological Correlation Between Pulp and Periapical Tissue Findings
M. Kovačević
T. Tamarut
S. Bešlić
S. Zoričić
D. Bobinac
Abstract
The aim of the study was to analyse the correlation between histopathological findings of pulp and periapical tissue during open infection of the pulp on the experimental dog model.
Nine mongrel dogs were divided into 4 experimental groups. Pulps of mandibular premolars (37 roots) were exposed using low-speed dental engine. Teeth were left open to the oral environment for 20 days (group I - two animals with eight roots), 35 days (group II - three animals with 15 roots), 50 days (group III - two animals with 6 roots) ahd 65 days (group IV - two animals with eight roots) to induce pulpitis and apical parodontitis. Pulp of the mesial root (nine roots) of a mandibular molar (control tooth) were not exposed to the oral environment. After the experimental period animals were sacrificed. Undemineralized teeth with bone, embedded in methylmetacrylate, were prepared for histological analysis (toluidine blue).
After 20 days exposure (group I9 six roots had partial pulp necrosis and two roots complete pulp necrosis. In group II (35 days exposure) three pulps had pulpitis, six roots had complete pulp necrosis and six partial pulp necrosis. In group III (50 days exposure) two roots had pulpitis, three partial pulp necrosis and one complete pulp necrosis. In group IV (65 days) all pulps (eight) had complete pulp necrosis. All teeth had pulpitis (five roots), regardless of the experimental period, had acute serose apical periodontitis in periapical tissue, all teeth (15 roots) with partial necrosis had subacute apical periodontitis in the periapical tissue. Teeth with complete pulp necrosis (19 roots) had chronic apical periodontitis and in one case in group III abscessus periapicalis. Correlation between histopathological findings of the pulp and periapical tissue is statistically significant (Pearson correlation; r = 0.92, p < 0.01).
The condition of the pulp correlated with the histopathological findings of periapical tissue in the open types of the pulp infection. Acute apical periodontitis with bone resorption began during pulpitits and can occur before 20 days of the pulp exposure in the dog.
Keywords
Hrčak ID:
3411
URI
Publication date:
15.9.2003.
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