Original scientific paper

Hepatotoxic potential of malathion in the freshwater teleost, Labeo rohita (Hamilton)

Vineetkumar Kallappa Patil ; Karnatak University Research Laboratory, Toxicology Division, Department of Zoology, Karnatak Science College, Dharwad, Karnataka, I
Muniswamy David ; Karnatak University Research Laboratory, Toxicology Division, Department of Zoology, Karnatak Science College, Dharwad, Karnataka, I

Abstract

Freshwater edible fi sh, Labeo rohita, were exposed to a sublethal concentration (0.9 μl/L) of commercial grade malathion (50% Emulsifi ed Concentration) for 5, 15 and 25 d. After each exposure period, the liver was taken, to study biochemical alterations. An increase in free amino acid, protease activity and ACh levels, in contrast to decrement in total, structural and soluble proteins and AChE activity, were observed after 5 and l5 d exposure, but on 25 d exposure all the values came nearer to normal. Restoration of protein fractions, free amino acid, protease activity, ACh levels and AChE activity to normal implies that after 15 d of exposure there seems to exist an oscillatory phase in protein turnover towards a more synthetic phase, leading to the establishment of recuperation and adaptation phenomena.

Keywords

Labeo rohita; liver toxicity; malathion

Hrčak ID:

37427

URI

https://hrcak.srce.hr/37427

Publication date:

20.4.2009.

Article data in other languages: croatian

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