Short communication, Note
https://doi.org/10.2478/10004-1254-60-2009-1925
In vitro Genotoxicity of Settat Town Landfill Leachate, Morocco
Loubna Amahdar
; Agrofood and Health Laboratory, Faculty of Science and Technology, University Hassan I, Settat, Morocco
Abdellah Anouar
; Agrofood and Health Laboratory, Faculty of Science and Technology, University Hassan I, Settat, Morocco
Bouchra Ababou
; Agrofood and Health Laboratory, Faculty of Science and Technology, University Hassan I, Settat, Morocco
Luc Verschaeve
; Laboratory of Toxicology, Scientifi c Institute of Public Health, Brussels, Belgium
Abderraouf Hilali
orcid.org/0000-0003-0221-9914
; Agrofood and Health Laboratory, Faculty of Science and Technology, University Hassan I, Settat, Morocco
Abstract
With the increasing use of landfill sites, leachates produced by uncontrolled waste disposal have became a serious threat for the aquatic environment. The aim of this study was to evaluate the genotoxicity of leachate and of well water sampled close to the town of Settat in Morocco using the micronucleus test and proliferation kinetics of human peripheral blood lymphocytes in vitro. We also analysed a number of physical and chemical parameters, including pH, % O2, chemical oxygen demand (COD), HCO3-, Ca2+, Mg2+, Cl-, and conductivity. The analysis showed much higher levels of nearly all parameters than the Moroccan standard. Increased micronucleus frequencies were also found for both leachate and well water. Preliminary results indicate that both types of water are genotoxic and pose environmental and human health risk.
Keywords
dose-effect; lymphocyte; micronucleus; physico-chemical properties; proliferation index; toxicity
Hrčak ID:
38399
URI
Publication date:
12.6.2009.
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