Acta Pharmaceutica, Vol. 56 No. 1, 2006.
Short communication, Note
Properties of the copper(II)-histidine complex obtained after dialysis of human plasma with histidine
TONY VENELINOV
SONIA ARPADJAN
IRINA KARADJOVA
JOHN BEATTIE
Abstract
The copper(II)-histidine complex obtained following dialysis of human plasma with histidine was investigated using various types of extraction systems and ion exchange resins. According to the results obtained, the Cu(II)-histidine complex formed under the dialysis conditions has one positive charge. Preconcentration of copper from the dialysis solution was achieved by its extraction as a dithiocarbamate complex and by sorption on cation-exchange resin or onto chelate sorbent.
Keywords
copper-histidine; human plasma dialysis; extraction; ion-exchange
Hrčak ID:
4569
URI
Publication date:
1.1.2006.
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