Original scientific paper

Multiple anthelmintic resistance in gastrointestinal nematodes of sheep in Southern India

Chinnakaruppiah Easwaran ; Department of Veterinary Parasitology, Veterinary College and Research Institute, Namakkal, India
Tirunelveli Jeyagopal Harikrishnan ; Department of Veterinary Parasitology, Veterinary College and Research Institute, Namakkal, India
Muthusamy Raman ; Department of Veterinary Parasitology, Veterinary College and Research Institute, Namakkal, India

Abstract

The occurrence of anthelmintic resistance on three institutional sheep farms in Tamil Nadu, India was investigated using the Faecal Egg Count Reduction Test (FECRT) for both benzimidazoles and levamisole, the egg hatch assay for benzimidazole (BZD) and Larval Migration Inhibition Assay (LMIA) for levamisole (LEV). FECR value after treatment with albendazole and levamisole ranged from 69-80 and from 70-82 respectively in the three farms examined. The ED50 values for TBZ in EHA for isolates from three farms were 0.627, 0.678 and 0.388 μg/mL of TBZ and the LM50 values in LMIA for the isolates from three farms were 0.707, 0.437 and 0.377 μg/mL of LEV. The results of the survey indicated multiple resistance in Haemonchus contortus and Teladorsagia sp. to benzimidazoles and levamisole in farm I, simultaneous resistance in Teladorsagia sp. to benzimidazoles and levamisole in farm II and simultaneous resistance in Haemonchus contortus to benzimidazoles and levamisole in farm III.

Keywords

Haemonchus contortus; Teladorsagia sp.; benzimidazoles; levamisole; resistance

Hrčak ID:

53091

URI

https://hrcak.srce.hr/53091

Publication date:

18.12.2009.

Article data in other languages: croatian

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