Conference paper

C-REACTIVE PROTEIN AND METABOLIC SYNDROME IN PATIENTS WITH BIPOLAR DISORDER COMPARED TO PATIENTS WITH SCHIZOPHRENIA

Bjanka Vuksan-Ćusa ; Department of Psychiatry, University Hospital Centre Zagreb, Croatia
Marina Šagud ; Department of Psychiatry, University Hospital Centre Zagreb, Croatia
Miro Jakovljević ; Department of Psychiatry, University Hospital Centre Zagreb, Croatia

Abstract

Introduction: Infectious and inflammatory processes could potentially play an important role in the etiology and pathogenesis of psychotic disorders. The aim was to investigate is there any differences in CRP levels in patients with bipolar disorder compared to patients with schizophrenia and if there is an association beetwen increased CRP levels and the presence of MS in theese two groups of patients.
Subjects and methods: Patients with bipolar disorder (N=60; 32 males and 28 females) and schizophrenia (N=63, 33 males and
30 females). MS was defined according to NCEP ATP III criteria. The cut-off point for elevated CRP was set at 5 mg /L.
Results: The prevalence of the MS was 31% in bipolar group compared to the 37% in schizophrenia group. No statistically
significant differences in mean CRP values was observed between bipolar and schizophrenia group. CRP >5 mg /l was significantly
associated with the presence of MS.
Conclusion: Measurement of serum inflammatory parameters in psychiatric patients may be beneficial in order to obtain a
better assessment of their metabolic risk profile.

Keywords

c-reactive protein; metabolic syndrome; bipolar disorder; schizophrenia

Hrčak ID:

55698

URI

https://hrcak.srce.hr/55698

Publication date:

30.6.2010.

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