Original scientific paper

Metabolic Evaluation of Urolithiasis Patients from Eastern Croatia

Vesna Babić-Ivančić
Selma CvijetićAvdagić
Vatroslav Šerić
Jasminka Kontrec
Antun Tucak
Helga Füredi-Milhofer
Milenko Marković

Abstract

Metabolic parameters were determined in fasting blood serum, fasting first morning urine, and 24-hour urine of male patients with recurrent calcium oxalate stones (N=26, age 39.1±6.2 years) as well as in male healthy controls (N=18, age 35.0±7.1 years), recruited from the eastern part of Croatia. The 24-hour urinary calcium excretion was significantly higher (p<0.01) for patients (5.6±2.5 mmol) than for controls (3.7±1.9 mmol), but potassium excretion was higher (p<0.01) for controls (74.5±33.8 mmol) than for patients (49.2±15.7 mmol). The mean ionic activity product of calcium and oxalate ions, IAP(CaOx), calculated from the fasting first morning urine parameters, was 25% higher for patients than for controls, but the difference was not statistically significant (p>0.05). Very strong correlation (r=0.97) was obtained between IAP(CaOx) values and calculated Ogawa indices that were recommended for estimating the potential risk for calcium oxalate stone formation.

Keywords

metabolic parameters; urine; calcium oxalate; urolithiasis; hypercalciuria; hyperoxaluria

Hrčak ID:

5590

URI

https://hrcak.srce.hr/5590

Publication date:

15.12.2004.

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