Original scientific paper

Systemic inflammatory response syndrome and multiple organ dysfunction syndrome in canine babesiosis

Vesna Matijatko ; Clinic for Internal Diseases, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Ivana Kiš ; Clinic for Internal Diseases, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Marin Torti ; Clinic for Internal Diseases, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Mirna Brkljačić ; Clinic for Internal Diseases, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Renata Barić Rafaj ; Department of Chemistry and Biochemistry, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Zdravko Žvorc ; Clinic for Internal Diseases, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Vladimir Mrljak ; Clinic for Internal Diseases, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia

Abstract

Canine babesiosis caused by Babesia canis canis is one of the commonest canine diseases in Croatia, especially in the area of capital city, Zagreb. Babesiosis is a multi-system disease and multiple organ dysfunction syndrome (MODS) develops from systemic inflfl ammatory response syndrome (SIRS), which is a hallmark of babesiosis. Therefore, the purpose of this study was to conduct detailed research of the incidence of SIRS and MODS as well as organ systems involvement in a large number of dogs naturally infected with B. canis canis in Croatia. Out of 332 dogs with canine babesiosis, 226 dogs (68 percent) fulfilled the SIRS criteria and were considered as SIRS positive. Among them 151 dogs (67%) fulfilled two SIRS criteria, 66 dogs (29%) fulfilled three criteria and only 9 dogs (4%) fulfilled all four SIRS criteria. Thirty-three dogs (10%) fulfilled the MODS criteria. Among them 22 dogs (66%) had two organ involvement, 10 dogs (31%) had three organ involvement and in only 1 dog (3%) four organ dysfunction was present. The incidence of organ involvement in MODS was as follows: renal dysfunction (30/33), liver dysfunction (20/33), muscle involvement (19/33), lung dysfunction (16/33), cerebral involvement (3/33). Among MODS positive dogs, 22 dogs died and 11 dogs survived babesiosis. In dogs with two organ involvement, survival was 45%, in dogs with three organ involvement survival was 10%, while in the group with four organ dysfunction mortality was 100%. It can be concluded that in cases of canine babesiosis caused by B. canis canis, in which MODS developed, an unfavourable outcome should be taken into consideration.

Keywords

babesiosis; dog; systemic inflammatory response syndrome; multiple organ dysfunction syndrome

Hrčak ID:

62147

URI

https://hrcak.srce.hr/62147

Publication date:

26.10.2010.

Article data in other languages: croatian

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