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Gynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics, Vol. 17 No. 3, 2008.

Original scientific paper

MATERNAL OBSTETRIC RISK FACTORS AND EARLY-ONSET NEONATAL SEPSIS

Amela Selimović ; Klinika za ginekologiju i akušerstvo, Odjeljenje za novorođenčad,Univerzitetsko klinički centar, Tuzla
Fahrija Skokić ; Klinika za ginekologiju i akušerstvo, Odjeljenje za novorođenčad, Univerzitetsko klinički centar, Tuzla
Zijad Selimović ; Klinika za kirurgiju, Odjeljenje urologije,** Univerzitetsko klinički centar, Tuzla

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Abstract

The common maternal obstetric risk factors associated with early-onset neonatal sepsis (EONS) include: premature rupture of membranes (>18 hours), maternal chorioamnionitis, urinary tract infection in pregnancy and intrapartum fever. The aim of study was to analyse various maternal obstetric risk factors to determine its effects on early-onset neonatal sepsis (EONS) in a tertiary care neonatal unit of Clinic for Gynecology and Obstetrics, Tuzla. Methods. Relevant data of analysed neonates born from January, 2004 to December, 2006 were obtained from their case records. A diagnosis of EONS was made if neonate had positive culture (blood, urine or cerebrospinal fluid), or clinical, or laboratory findings consistent with sepsis within 72 hours of life. Results. Of the 341 neonates with one ore more maternal obstetric risk factors, 199 (58,4%) developed EONS. The incidence of EONS among neonates with the premature rupture of membranes was 93/199 (46,7%) with low OR 0,178 and 95%CI (0,101–0,307). Intrapartum fever was related to EONS among 40/199 (20,1%) neonates, with high OR:3,717 and 95%CI:1,691–9,008. Maternal chorioamnionitis and excessive vaginal discharge were the causes of EONS in the same per cent (15,6%), while OR was high for maternal chorioamnionitis (4,182 and 95%CI (1,648–12,580)), and low for excessive vaginal discharge (1,271 and 95%CI (0,654–2,529)). EONS occurred among 35/199 (17,6%) neonates whose mothers had urinary tract infection in pregnancy, with high OR of 4,115 and 95%CI:1,723–11,729. Conclusion. The possibility of early-onset neonatal sepsis is high among neonates with maternal obstetric risk factors, especially with chorioamnionitis, urinary tract infection in pregnancy and intrapartum fever.

Keywords

neonate; sepsis; obstetric risk factors

Hrčak ID:

62189

URI

https://hrcak.srce.hr/62189

Publication date:

1.9.2008.

Article data in other languages: croatian

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