Editorial
SELF-REPORTED MEDICATION ADHERENCE CORRELATES WITH PHOSPHATE LEVELS, RESIDUAL DIURESIS AND NUTRITIONAL STATUS IN HEMODIALYSIS PATIENTS: AN INTERNATIONAL MULTICENTER STUDY
LEA KATALINIĆ
; Zagreb University Hospital Centre, Zagreb, Croatia
NIKOLINA BAŠIĆ-JUKIĆ
; Zagreb University Hospital Centre, University of Zagreb, School of Medicine, Zagreb,3Josip Juraj Strossmayer University of Osijek, School of Medicine, Osijek, Croatia
HALIMA RESIĆ
; Sarajevo University Hospital Centre, Sarajevo, Bosnia and Herzegovina
BOŽIDAR VUJIČIĆ
; Zagreb University Hospital Centre, Zagreb,Rijeka University Hospital Centre, Rijeka,Croatia
BORIS KUDUMIJA
; Avitum Dialysis Centre, Zagreb, Croatia
MARINA RATKOVIĆ
; Montenegro University Hospital Centre, Podgorica, Montenegro
LEMS JERIN
; Avitum Dialysis Centre, Zagreb, Croatia
VLADIMIR PRELEVIĆ
; Montenegro University Hospital Centre, Podgorica, Montenegro
DANILO RADUNOVIĆ
; Montenegro University Hospital Centre, Podgorica, Montenegro
BRANIMIR KRTALIĆ
; University of Zagreb, School of Medicine, Zagreb, Croatia
TAMARA KNEŽEVIĆ
; Zagreb University Hospital Centre, Zagreb, Croatia
MONIKA KOCMAN
; Zagreb University Hospital Centre, Zagreb, Croatia
SANJIN RAČKI
; Rijeka University Hospital Centre, Rijeka, Croatia
Abstract
Compliance is a major obstacle to achieving phosphorus control in the majority of patients with end-stage renal disease. We investigated self-reported medication adherence and its correlation with serum phosphate levels and nutritional status in hemodialysis patients. A total of 417 patients from Croatia, Montenegro and Bosnia and Herzegovina, mean age 63.82 (range, 21-92) years, were included in the study. There were 55.1% of male patients with the mean dialysis vintage of
68.67 (range, 3-456) months. A signifi cant positive correlation was found between self-reported adherence and serum phosphorus (0.192), and negative correlation with hemoglobin, prealbumin, albumin, Kt/V and residual diuresis (-0.187, -0.227, -0.100, 0.192, and -0.106, respectively). On the other hand, the number of pills taken daily correlated signifi cantly with residual diuresis, serum prealbumin, serum glucose, triglycerides, ferritin and ultrafi ltration volume (0.241, 0.154, 0.158, 0.112, 0.201 and 0.125, respectively). In conclusion, self-reported medication adherence correlates with serum phosphate levels, residual diuresis and nutritional status in hemodialysis patients.
Keywords
medication adherence; phosphate level; nutritional status; pill burden
Hrčak ID:
193665
URI
Publication date:
13.2.2018.
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