Skoči na glavni sadržaj

Fizikalna i rehabilitacijska medicina, Vol. 21 No. 1-2, 2007.

Pregledni rad

Early diagnosis of rheumatoid arthritis

Đurđica BABIĆ-NAGLIĆ ; Klinika za reumatske bolesti i rehabilitaciju Klinički bolnički centar Zagreb, Kišpatićeva 12, Zagreb
Iva ŽAGAR ; Klinika za reumatske bolesti i rehabilitaciju Klinički bolnički centar Zagreb, Kišpatićeva 12, Zagreb

Puni tekst: hrvatski pdf 119 Kb

str. 10-16

preuzimanja: 821

citiraj

Puni tekst: engleski pdf 119 Kb

str. 10-16

preuzimanja: 2.486

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Sažetak

Rheumatoid arthritis (RA) is chronic joint disease which if untreated leads to permanent structural damage and disability. Early diagnosis and therapy are the main requests for good clinical practice. Early diagnosis tools include specific clinical assesment, serological, immunogenetic and radiological evaluation. Disease activity score is cornerstone in clinical assesment, rheumatoid factor and anti-cyclic
citrullinated peptide antibodies (anti-CCP) are very specific serological parameters. The shared epitope containing HLA-DRB1 alleles represent the most significant genetic risk for RA. Magnetic resonance and ultrasound imaging are very sensitive methods for erosion detection in early phase of the disease.

Ključne riječi

rheumatoid arthritis; early diagnosis; anti-CCP; HLA-DRB1

Hrčak ID:

129198

URI

https://hrcak.srce.hr/129198

Datum izdavanja:

28.7.2006.

Podaci na drugim jezicima: hrvatski

Posjeta: 4.852 *