Liječnički vjesnik, Vol. 138 No. 5-6, 2016.
Original scientific paper
PATHOLOGICAL CHANGES OF RENAL ARTERIES IN PATIENTS WITH RENAL CELL CARCINOMA
Alma Demirović
Hrvoje Čupić
Božo Krušlin
Abstract
Renal cell carcinoma is the ninth most common cancer in the world. It may have a varied microscopic appearance, and the most common histopathological type is clear cell carcinoma. The most common pathological changes of renal arteries are atherosclerosis and fibromuscular dysplasia (FMD). During histopathological evaluation of a kidney specimen containing carcinoma, the renal vein is routinely analyzed, while the renal artery is usually given little attention. Our studies have shown that pathological changes of renal arteries are significantly more frequent in the group of patients with renal cell carcinoma compared with the control group and the group of patients with non-tumor kidney diseases. These relations led us to the conclusion that the onset of renal artery changes is not prior to the carcinoma or non-tumor diseases and that they are formed simultaneously or as a consequence. Further studies should be aimed at determining the incidence of these changes in a larger number of samples and the detection of their possible correlation with renal cell carcinoma.
Keywords
Carcinoma, renal cell – complications, pathology; Kidney neoplasms – complications, pathology; Renal artery – pathology; Atherosclerosis – etiology, pathology; Fibromuscular dysplasia – etiology, pathology; Necrosis – pathology
Hrčak ID:
172852
URI
Publication date:
30.6.2016.
Visits: 2.058 *