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Hrana u zdravlju i bolesti : znanstveno-stručni časopis za nutricionizam i dijetetiku, Vol. 13 No. 2, 2024.

Izvorni znanstveni članak

SIMULATION OF GLUCOSE AND INSULIN KINETICS MODEL USING THE GLYCEMIC LOAD OF MIXED MEALS

Sara Maraš ; University of Zagreb Faculty of Food Technology and Biotechnology, Pierottijeva 6, 10000 Zagreb, Croatia
Davor Valinger ; University of Zagreb Faculty of Food Technology and Biotechnology, Pierottijeva 6, 10000 Zagreb, Croatia
Tea Sokač Cvetnić ; University of Zagreb Faculty of Food Technology and Biotechnology, Pierottijeva 6, 10000 Zagreb, Croatia
Tamara Jurina ; University of Zagreb Faculty of Food Technology and Biotechnology, Pierottijeva 6, 10000 Zagreb, Croatia
Maja Benković ; University of Zagreb Faculty of Food Technology and Biotechnology, Pierottijeva 6, 10000 Zagreb, Croatia
Jasenka Gajdoš Kljusurić ; University of Zagreb Faculty of Food Technology and Biotechnology, Pierottijeva 6, 10000 Zagreb, Croatia
Ana Jurinjak Tušek ; University of Zagreb Faculty of Food Technology and Biotechnology, Pierottijeva 6, 10000 Zagreb, Croatia *

* Dopisni autor.

Puni tekst: engleski pdf 737 Kb

str. 67-75

preuzimanja: 3

citiraj

Sažetak

This study aimed to assess how the glycemic load in various mixed meals affects glucose and insulin levels using a mathematical model of glucose and insulin dynamics. Three distinct dietary menus were formulated (high-carbohydrate, diabetic, and low-carbohydrate) each with calculated glycemic loads. The model was then simulated using the WR Mathematica 10.0 software using the data form developed menus. Findings revealed that meals with a high glycemic load significantly influenced blood glucose and insulin levels. Additionally, a negative correlation was observed between carbohydrate proportions and protein
(r = -0.9500) as well as fat (r = -0.9855) proportions in the meals. The glycemic load of a single meal can serve as an initial value for simulating the glucose-insulin metabolism model, enabling a personalized approach to meal development through the application of the primary nutrient metabolism model.

Ključne riječi

mathematical model of glucose and insulin kinetics; glycemic load; glucose concentration; model simulation

Hrčak ID:

325951

URI

https://hrcak.srce.hr/325951

Datum izdavanja:

31.12.2024.

Posjeta: 7 *