Professional paper
CLINICAL CHARACTERISTICS OF BLADDER CANCER PATIENTS TREATED WITH CYSTECTOMY: THREE-YEAR EXPERIENCE FROM THE CLINICAL HOSPITAL CENTER RIJEKA
BERNARD NOVIĆ
; Faculty of Medicine, University of Rijeka, Rijeka, Croatia
*
LICIJA KUČINA
; Faculty of Medicine, University of Rijeka, Rijeka, Croatia
KRISTIAN KRPINA
; Faculty of Medicine, University of Rijeka, Rijeka, Croatia; Department of Urology, Clinical Hospital Center Rijeka, Rijeka, Croatia
IVONA JERKOVIĆ
; Department of Oncology, Clinical Hospital Center Rijeka, Rijeka, Croatia
DEAN MARKIĆ
; Faculty of Medicine, University of Rijeka, Rijeka, Croatia; Department of Urology, Clinical Hospital Center Rijeka, Rijeka, Croatia
* Corresponding author.
Abstract
The objective of the study was to present clinical characteristics of patients operated for bladder cancer in our center.
Methods: In this retrospective study we present patients who underwent radical cystectomy due to bladder cancer. All patients
were operated at the Department of Urology, Clinical Hospital Center Rijeka, between 2017 and 2019. Their demographic and
clinical characteristics were analyzed. Results: In the observed three-year period radical cystectomy was performed in 96 patients
due to muscle-invasive bladder cancer or high-risk non-muscle-invasive bladder cancer. Of these, 74 (77.1 %) were men, and 22
(22.9 %) were women. Seventy-five patients (78.1 %) were 65 years old or older. Ureterocutaneostomy was performed in 46 (47.9
%) patients, neobladder in 27 (28.1 %) patients, and ileum conduit according to Bricker in 20 (20.8 %) patients. The definitive
pathohistological finding was carcinoma in situ in 4 (4.2 %) patients, pT1 in 11 (11.5 %), pT2 in 31 (32.3 %), pT3 in 27 (28.1 %),
and pT4 in 23 (23.9 %) patients. At the time of the surgery locally advanced disease was present in 43 (44.8 %) and metastatic
disease in 17 (17.7 %) patients. Neoadjuvant chemotherapy was administered in 4 (4.2 %) patients, adjuvant chemotherapy
in 13 (13.5 %), and radiotherapy in 18 (18.8 %) patients. Conclusion: Bladder cancer was more frequently found in male and
elderly patients. Ureterocutanostomy was the most frequent type of urinary diversion. Oncological treatment was necessary
in approximately one third of the patients.
Keywords
radical cystectomy; urinary bladder tumors; chemotherapy; urinary diversion
Hrčak ID:
331223
URI
Publication date:
16.5.2025.
Visits: 263 *