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Acta clinica Croatica, Vol. 64. No. 2, 2025.

Original scientific paper

https://doi.org/10.20471/acc.2025.64.02.02

Localized Pigmented Villonodular Synovitis of the Knee: A Consecutive Case Series and Review of the Literature

Ivan Bojanić orcid id orcid.org/0000-0002-4236-9637 ; Department of Orthopedic Surgery, Zagreb University Hospital Center, Zagreb, Croatia; University of Zagreb, School of Medicine, Zagreb, Croatia *
Ivan Levaj ; Department of Orthopedic Surgery, Zagreb University Hospital Center, Zagreb, Croatia
Damjan Dimnjaković ; Department of Orthopedic Surgery, Zagreb University Hospital Center, Zagreb, Croatia
Tomislav Smoljanović ; Department of Orthopedic Surgery, Zagreb University Hospital Center, Zagreb, Croatia; University of Zagreb, School of Medicine, Zagreb, Croatia

* Corresponding author.

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Abstract

Pigmented villonodular synovitis is a rare disease that occurs on synovial tissue within
and outside a joint. It can be localized or diffuse. Localized pigmented villonodular synovitis (LPVNS)
can occur in any compartment of the knee joint. The aim of this study was to retrospectively analyze our
consecutive series of LPVNS of the knee. From January 1999 to December 2018, 10 consecutive patients
with LPVNS of the knee underwent surgical treatment at our department. All patients were arthroscopically
treated by the senior author by removal of the localized mass and partial synovial resection of the
area surrounding the bottom of the lesion. The series included four female and six male patients, mean
age 29.5 (range, 17-60) years. Their symptoms prior to the operation lasted from 3 months to 3 years
(mean, 11.8 months). At the mean follow-up of 110.9 (range, 11-239) months, none of the patients had
recurrence of the disease. Our study confirms the consensus in the literature that LPVNS of the knee
should be treated arthroscopically by excision of the localized mass and partial synovectomy of the area
surrounding the base of the lesion.

Keywords

Pigmented villonodular synovitis; Localized pigmented villonodular synovitis; Knee; Arthroscopy

Hrčak ID:

337440

URI

https://hrcak.srce.hr/337440

Publication date:

30.6.2025.

Article data in other languages: croatian

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