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Review article

Regulation of the Cyanide-Resistant Alternative Respiratory Pathway in the Fungus Acremonium chrysogenum

Erzsébet Sándor ; Department of Microbiology and Biotechnology, Faculty of Sciences, University of Debrecen, H-4010, P.O.Box 63, Debrecen, Hungary
Erzsébet Fekete ; Department of Microbiology and Biotechnology, Faculty of Sciences, University of Debrecen, H-4010, P.O.Box 63, Debrecen, Hungary
Levente Karaffa ; Department of Microbiology and Biotechnology, Faculty of Sciences, University of Debrecen, H-4010, P.O.Box 63, Debrecen, Hungary


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Abstract

This review summarises the current knowledge on the biochemical and physiological events that directly or indirectly alter the engagement of the cyanide-resistant alternative respiratory pathway in the cephalosporin C producer filamentous fungus Acremonium chrysogenum. Particular emphasis is placed on the role this activity plays in the overproduction of antibiotic, and also on the critical fermentation technology background that supports its operation.

Keywords

Acremonium chrysogenum; alternative oxidase; respiration; peroxides; cephalosporin C; soybean oil

Hrčak ID:

110942

URI

https://hrcak.srce.hr/110942

Publication date:

17.3.2003.

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