Review article
Regulation of the Cyanide-Resistant Alternative Respiratory Pathway in the Fungus Acremonium chrysogenum
Erzsébet Sándor
; Department of Microbiology and Biotechnology, Faculty of Sciences, University of Debrecen, H-4010, P.O.Box 63, Debrecen, Hungary
Erzsébet Fekete
; Department of Microbiology and Biotechnology, Faculty of Sciences, University of Debrecen, H-4010, P.O.Box 63, Debrecen, Hungary
Levente Karaffa
; Department of Microbiology and Biotechnology, Faculty of Sciences, University of Debrecen, H-4010, P.O.Box 63, Debrecen, Hungary
Abstract
This review summarises the current knowledge on the biochemical and physiological events that directly or indirectly alter the engagement of the cyanide-resistant alternative respiratory pathway in the cephalosporin C producer filamentous fungus Acremonium chrysogenum. Particular emphasis is placed on the role this activity plays in the overproduction of antibiotic, and also on the critical fermentation technology background that supports its operation.
Keywords
Acremonium chrysogenum; alternative oxidase; respiration; peroxides; cephalosporin C; soybean oil
Hrčak ID:
110942
URI
Publication date:
17.3.2003.
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