Acta clinica Croatica, Vol. 43 No. 1, 2004.
Other
Askin's Tumor - A Rare Tumor of the Thoracopulmonary Region
Anto Bekić
Muharem Mehulić
Marijan Gorečan
Suzana Kukulj
Diana Krmpotić
Merica Veir
Abstract
Askin's tumor is a malignant small round cell tumor affecting the thoracopulmonary region. Because of its neuroectodermal origin it is also known as primitive neuroectodermal tumor. This rarely seen and aggressive malignant tumor most frequently occurs in children and young adults. The symptoms and clinical presentation as well as radiomorphologic abnormalities are nonspecific. Therefore, establishing an accurate diagnosis of Askin's tumor is difficult, thus histologic and immunohistologic findings are important. Immunohistologic stain of the specific marker neuron-specific enolase is essential. In addition, Askin's tumor shows histologic features similar to Ewing's tumor located in the bones, which suggests it to belong to the group of Ewing's tumors. Therapeutic approach is multimodal, e.g., surgical resection, chemotherapy, and radiation. Overall prognosis is poor. The objective of this report is to point to this unusual tumor of the thoracopulmonary region. A 23-year-old female with a giant right chest tumor mass and immunohistologic findings of the surgical specimen characteristic of Askin's tumor is described.
Keywords
Lung neoplasms - pathology; Lung neoplasms - histology; Lung neoplasms - diagnosis; Case report
Hrčak ID:
14443
URI
Publication date:
1.3.2004.
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