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Original scientific paper

The effect of lead on protein and lactate dehydrogenase activity in hepatic slices cultured in vitro

E.J. Kucharz ; Department of Clinical Chemistry and Laboratory Diagnostics and Department of Pathology, Silesian School of Medicine, Katowice, Poland
B. Stawiarska-Pieta ; Department of Clinical Chemistry and Laboratory Diagnostics and Department of Pathology, Silesian School of Medicine, Katowice, Poland


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Abstract

Slices of foetal and adult liver were cultured in vitro with various concentrations of Iead ions. A decrease in protein content and an increase in lactate dehydrogenase activity in the culturing medium were found. The changes were dose-dependent, and the foetal liver tissue was found to be more susceptible to the effect of lead than the tissue of adult rats.

Keywords

Hrčak ID:

153812

URI

https://hrcak.srce.hr/153812

Publication date:

24.2.1987.

Article data in other languages: croatian

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