Meeting abstract
HERBAL PRODUCTS AS POTENTIAL THERAPY FOR FUNCTIONAL DYSPEPSIA
Ivan Vukoja
; County Hospital Požega, Osječka 107, 34000 Požega, Croatia
Anita Galić
; Croatian Pharmaceutical Society, Masarykova 2/II, 10000 Zagreb, Croatia
Anamarija Jurić
; County Hospital Požega, Osječka 107, 34000 Požega, Croatia
Goran Zukanović
; County Hospital Požega, Osječka 107, 34000 Požega, Croatia
Martina Brus Škrljac
; County Hospital Požega, Osječka 107, 34000 Požega, Croatia
Jasmina Kovačević
; Institute of Public Health Pozega-Slawonia County, Županijska 9, 34000 Požega, Croatia
Abstract
Functional dyspepsia (FD) is defined as the presence of postprandial fullness, early satiation, epigastric
burning or pain in the absence of other systemic, metabolic or organic disease. FD is divided in post-
3
Sažeci radova / Abstracts
prandial distress syndrome (PDS) and epigastric pain syndrome (EPS) with significant overlap with
gastroesophageal reflux disease (GERD) and irritable bowel syndrome (IBS) symptoms. Current recommended
therapy is antisecretory drugs (PPIs or H2RAs), but recurrence of symptoms is often after intermission
of therapy. Prokintetic drugs such as metoclopramide and domperidone are especially effective
in PDS, but like antisecretory drugs long term therapy is not recommended. Acotiamide could be effective
as prokinetics. Antidepressants (SSRI) show some results as well as bismuth salts and simethicone
but adequate trials are needed. Various numbers of Chinese, Korean and Iranian herbs are excluded from
this research. Alginates provide effects in GERD, but FD effects are doubtful. Data show that SWT5 is
effective as prokinetics, especially with IBS overlap. Peppermint and caraway oil, star anise, ginger and
artichoke leaf extracthave better efficacy than placebo in the treatment offunctional dyspepsia. Olive oil,
red pepper, curcuma, dandelion and Melissa could be useful, but well developed prospective clinical
trials are needed.
Keywords
Functional dyspepsia; herbal products; potential therapy
Hrčak ID:
198853
URI
Publication date:
31.12.2017.
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