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Croatica Chemica Acta, Vol. 91 No. 3, 2018.

Short communication, Note

https://doi.org/10.5562/cca3379

Content of Bioactive Constituents and Antioxidant Potential of Galium L. Species

Maja Friščić orcid id orcid.org/0000-0001-9404-2209 ; University of Zagreb, Faculty of Pharmacy and Biochemistry, Department of Pharmaceutical Botany, Schrottova 39, HR-10000 Zagreb, Croatia
Maja Štibrić Baglama ; ZU Ljekarne Pučko, Vladimira Nazora 25A, HR-44320 Kutina, Croatia
Milenko Milović orcid id orcid.org/0000-0003-0851-4869 ; Antun Vrančić Grammar School, Put Gimnazije 64, HR-22000 Šibenik, Croatia
Kroata Hazler Pilepić ; University of Zagreb, Faculty of Pharmacy and Biochemistry, Department of Pharmaceutical Botany, Schrottova 39, HR-10000 Zagreb, Croatia
Željan Maleš orcid id orcid.org/0000-0003-1034-2525 ; University of Zagreb, Faculty of Pharmacy and Biochemistry, Department of Pharmaceutical Botany, Schrottova 39, HR-10000 Zagreb, Croatia

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Abstract

Qualitative phytochemical analyses of eight species from the genus Galium (G. corrudifolium, G. cruciata, G. divaricatum, G. lucidum, G. mollugo, G. palustre, G. parisiense, and G. verum), followed by spectrophotometric evaluation of their total phenolic, flavonoid and iridoid content, as well as antiradical capacity, were conducted. G. cruciata contained the greatest amount of total phenolics (111.00 mg gallic acid equivalents g–1 dry extract), while G. verum had the greatest amount of flavonoids (23.11 mg quercetin equivalents g–1 dry extract) and iridoids (461.30 mg aucubin equivalents g–1 dry extract). The best antioxidant (antiradical) activity was shown by G. cruciata (IC50 (ABTS) = 30.30 µg mL–1; IC50 (DPPH) = 27.62 µg mL–1), followed by G. divaricatum, G. verum and G. palustre. The same species were rich in various bioactive constituents and would be appropriate for inclusion in further investigations considering their biomedical potential.

This work is licensed under a Creative Commons Attribution 4.0 International License.

Keywords

Galium; phytochemical screening; secondary metabolites; bioactive compounds; antioxidant activity

Hrčak ID:

203859

URI

https://hrcak.srce.hr/203859

Publication date:

29.12.2018.

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