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Acta clinica Croatica, Vol. 59. No. Supplement 1, 2020.

Review article

https://doi.org/10.20471/acc.2020.59.s1.11

Prophylactic Central Neck Dissection in Well-differentiated Thyroid Cancer

Krešimir Gršić orcid id orcid.org/0000-0002-2907-8640 ; Department of Otorhinolaryngology and head and neck surgery, Zagreb University Hospital Centre, Zagreb, Croatia
Boris Bumber orcid id orcid.org/0000-0003-1101-606X ; Department of Otorhinolaryngology and head and neck surgery, Zagreb University Hospital Centre, Zagreb, Croatia
Renata Curić Radivojević orcid id orcid.org/0000-0002-5984-617X ; Department of Anaesthesiology, Resuscitation and Intensive Care, Zagreb University Hospital Centre, Zagreb, Croatia
Dinko Leović ; Department of Otorhinolaryngology and head and neck surgery, Zagreb University Hospital Centre, Zagreb, Croatia; Department of Otorhinolaryngology and Maxillofacial Surgery, Faculty of Medicine, J. J. Strossmayer University of Osijek, Osijek, Croatia; Department of Dental Medicine, Faculty of Dental Medicine and Health

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Abstract

Well-differentiated cancers, both papillary and follicular, account for 90% of all
diagnosed thyroid cancers. They have an indolent disease course with a 20-year disease-specific survival
over 90%. According to current guidelines, the therapy of choice for well-differentiated thyroid
carcinoma is total thyroidectomy or lobectomy. The indication for prophylactic central neck dissection
is still a controversial issue and the subject of unfinished and ongoing debate. There is no indication
for prophylactic central neck dissection in follicular thyroid carcinomas, which primarily metastasize
hematogenously. In small solitary papillary thyroid carcinomas (T1 and T2), prophylactic central neck
dissection is not indicated as it does not bring benefits in terms of improved patient survival and at the
same time significantly increases the risk of temporary and permanent postoperative complications.
Prophylactic central neck dissection is indicated in advanced papillary thyroid cancers (T3 and T4)
and all other high-risk well-differentiated thyroid cancer, as well as in the presence of metastatic
lymph nodes in the lateral neck.

Keywords

differentiated thyroid cancer; papillary thyroid cancer; follicular thyroid cancer; prophylactic central neck dissection; surveillance

Hrčak ID:

248276

URI

https://hrcak.srce.hr/248276

Publication date:

1.11.2020.

Article data in other languages: croatian

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