Original scientific paper
Polycystic Ovary Syndrome and Infertility: A Retrospective Cross-Sectional Study
Nada Gruja
; University Department of Nursing Catholic University of Croatia Zagreb, Croatia
Ana Tikvica Luetić
; University Department of Nursing Catholic University of Croatia
*
* Corresponding author.
Abstract
Background: Polycystic ovary syndrome (PCOS) is the most common endocrinological and reproductive-metabolic disorder in women, characterized by chronic ovulatory dysfunction, oligomenorrhea, hyperandrogenism and infertility. Infertility, the absence of a desired pregnancy with regular, unprotected intercourse for a period of at least one year, is a major public health problem today.
Aim: The aim of this retrospectively registered study was to examine the hormonal characteristics of infertile patients
diagnosed with PCOS and compare them with a control group of infertile women not diagnosed with PCOS, of comparable ages and body mass indices. Methods: In this retrospective cross-sectional study, the subjects were thirty patients diagnosed with PCOS treated for infertility at the Department of Obstetrics and Gynecology, Sveti Duh Clinical Hospital, who were compared to a control group of women not diagnosed with PCOS but diagnosed with infertility, of comparable ages and body mass indices.
The data were collected from an electronic database, and the values of the observed indicators of the patients’ health status were presented in graphs and tables.
Results: The results show that there were statistically signifi cant differences in the levels of AMH, LH, E2 and FSH. In other words, the patients with PCOS had higher AMH and LH, and lower E2 and FSH, in comparison to women not diagnosed with polycystic ovaries of the comparable age and body mass indices. TSH and prolactin levels were
comparable between the two groups.
Conclusion: Our study confi rmed that infertile patients diagnosed with PCOS have different serum levels of pituitary and ovarian sex hormones in comparison to the controls.
Keywords
Polycystic ovary syndrome; infertility; hormones
Hrčak ID:
333395
URI
Publication date:
2.6.2024.
Visits: 106 *