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Review article

Neuroplasticity and brain neoplasms

Vanja Klarin orcid id orcid.org/0009-0001-6591-2735 ; School of Medicine, University of Zagreb, Zagreb, Croatia *
Marko Krklec orcid id orcid.org/0009-0004-4009-7449 ; School of Medicine, University of Zagreb, Zagreb, Croatia *

* Corresponding author.


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Abstract

Neuroplasticity is the ability of the brain to reorganize its networks to adapt to changes in neural surroundings. It is an important component of learning and memory, but it is also critical in the process of tissue recovery after brain injury. One of the most common causes of brain injury are tumors of the central nervous system. Thus, the importance of understanding the relationship between plasticity and injuries caused by brain tumors is apparent. Plastic reorganization can affect healthy motor and sensory regions, language networks, the hippocampus, and many other areas, as well as infiltrative neoplastic structures themselves. This literature review aims to analyze the different aspects of neuroplasticity as pertaining to brain neoplasms, in order to better understand the different implications of plastic processes in a tumor-afflicted brain. This understanding could be used to improve postoperative outcomes of resection, find new therapeutic methods, and reveal the mechanisms behind plasticity in disease conditions.

Keywords

brain networks; brain tumors; language; motor cortex; neuromodulation; neuroplasticity

Hrčak ID:

343399

URI

https://hrcak.srce.hr/343399

Publication date:

28.12.2025.

Visits: 397 *