Pregledni rad
https://doi.org/10.1515/aiht-2016-67-2837
Ectoine as a promising protective agent in humans and animals
Adam Bownik
; Department of Biological Basis of Animal Production, Faculty of Biology, Animal Sciences and Bioeconomy,University of Life Sciences in Lublin, Lublin, Poland
Zofia Stępniewska
; Department of Biochemistry and Environmental Chemistry, Faculty of Biotechnology and Environmental Sciences, John Paul II Catholic University of Lublin, Lublin, Poland
Sažetak
Ectoine is a compatible water molecule-binding solute (osmoprotectant) produced by several bacterial species in response to osmotic stress and unfavourable environmental conditions. This amino acid derivative can accumulate inside cells at high concentrations without interfering with natural processes and can protect the cell against radiation or osmotic stress. This brief review presents the current state of knowledge about the effects of ectoine on animals and focuses on its practical use for enzyme stabilisation, human skin protection, anti-inflammatory treatment, inhibitory effects in neurodegenerative diseases, and other therapeutic potential in human or veterinary medicine.
Ključne riječi
cell protection; compatible solute; macromolecular stability; osmoprotectant
Hrčak ID:
170507
URI
Datum izdavanja:
14.12.2016.
Posjeta: 4.113 *