Stručni rad
https://doi.org/10.15644/asc53/3/9
Oral Mucormycosis and Aspergillosis in the Patient with Acute Leukemia
Vanja Vučićević Boras
; Zavod za oralnu medicinu Stomatološkog fakulteta Sveučilišta u Zagrebu i Klinički zavod za bolesti usta Kliničkog bolničkog centra Zagreb, Zagreb, Hrvatska
Martin Jurlina
; Klinika za bolesti uha, nosa i grla i kirurgiju glave i vrata Kliničkoga bolničkog centra Zagreb, Zagreb, Hrvatska
Vlaho Brailo
; Zavod za oralnu medicinu Stomatološkog fakulteta Sveučilišta u Zagrebu i Klinički zavod za bolesti usta Kliničkog bolničkog centra Zagreb, Zagreb, Hrvatska
Katarina Đurić Vuković
; Klinika za bolesti uha, nosa i grla i kirurgiju glave i vrata Kliničkoga bolničkog centra Zagreb, Zagreb, Hrvatska
Pavle Rončević
; Zavod za hematologiju Kliničkoga bolničkog centra Zagreb, Zagreb, Hrvatska
Sandra Bašić Kinda
; Zavod za hematologiju Kliničkoga bolničkog centra Zagreb, Zagreb, Hrvatska
Danica Vidović Juras
; Zavod za oralnu medicinu Stomatološkog fakulteta Sveučilišta u Zagrebu i Klinički zavod za bolesti usta Kliničkog bolničkog centra Zagreb, Zagreb, Hrvatska
Dragana Gabrić
; Zavod za oralnu kirurgiju Stomatološkog fakulteta Sveučilišta u Zagrebu i Klinički zavod za oralnu kirurgiju Kliničkoga bolničkog centra Zagreb, Zagreb, Hrvatska
Sažetak
A 54-year-old male patient with acute lymphoblastic leukemia was referred to the Department of Oral Medicine. He had a primary refractory disease and was treated according to HOVON71 and HAM protocol. Sixteen days after the start of the HAM protocol the patient developed palatal dark red/brownish lesion and maxillary vestibular exophytic lesion. Biopsy specimens from oral lesions were taken and microbiologic evaluation confirmed the presence of Aspergillus fumigatus and Rhizopus genus. The treatment of the patient consisted of the inferior maxillectomy and intravenous posaconazole and amphotericine B for the following 28 days. Since the coinfection with Aspergillus and Rhizopus is extremely rarely seen in the oral cavity, a diagnostic and therapeutic dilemma easily presents itself.
Ključne riječi
Mouth Diseases; Mucormycosis; Aspergillosis; Immunocompromised Host; Leukemia
Hrčak ID:
225689
URI
Datum izdavanja:
26.9.2019.
Posjeta: 5.175 *