Izvorni znanstveni članak

https://doi.org/10.20471/acc.2025.64.02.15

The Association of SYNTAX Score II with Lipid Profile, Serum Uric Acid Levels and Diabetes Mellitus in Patients with Multivessel Coronary Disease

Vedran Đambić ; Hyperbaric Medicine Unit, Slavonia Polyclinic, Osijek, Croatia; Department of Physiology and Immunology, Faculty of Medicine, Josip Juraj Strossmayer University in Osijek, Osijek, Croatia
Ivica Bošnjak ; Department of Cardiovascular Diseases, Osijek University Hospital Center, Osijek, Croatia
Dijana Dumančić ; Department of Diagnostic and Interventional Radiology, Osijek University Hospital Center, Osijek, Croatia
Aleksandar Kibel orcid.org/0000-0001-7843-1079 ; Department of Cardiovascular Diseases, Osijek University Hospital Center, Osijek, Croatia; Department of Physiology and Immunology, Faculty of Medicine, Josip Juraj Strossmayer University in Osijek, Osijek, Croatia; Scientific Center of Excellence for Personalized Health Care, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia *

* Dopisni autor.

Sažetak

The SYNTAX Score II (SS II) is a clinical tool that allows individualized prediction
of mortality in patients with multivessel coronary artery disease (CAD) treated with percutaneous coronary
intervention (PCI) or coronary artery bypass grafting (CABG). The aim was to examine whether
lipid profile, uric acid and diabetes had a positive correlation with higher values of SS II. The study
included 72 CAD patients. An online calculator was used to calculate SS II. Statistical tests (Mann
Whitney U test and Shapiro-Wilk test) were used to assess correlations and differences in lipid profile,
uric acid and diabetes status according to SS II values. There was a significant positive correlation between
the proportion of patients with HDL levels above the reference values and SS II PCI. Patients
with lower LDL values had significantly increased values of SS II CABG, but not SS II PCI. There was
no significant correlation of total cholesterol and triglycerides with SS II PCI or SS II CABG. Patients
with hyperuricemia had significantly higher SS II PCI but not SS II CABG. People with diabetes had
significantly increased SS II PCI but not SS II CABG compared to non-diabetic patients. In conclusion,
SS II is associated with some of the classic risk factors for atherosclerosis (uric acid, diabetes), whereas in
our patient cohort there was a surprising correlation of SS II with high HDL levels and low LDL levels.

Ključne riječi

Diabetes mellitus; Hyperuricemia; Lipid profile; Multivessel coronary disease; SYNTAX Score II

Hrčak ID:

337602

URI

https://hrcak.srce.hr/337602

Datum izdavanja:

30.6.2025.

Podaci na drugim jezicima: hrvatski

Posjeta: 147 *