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Elevated Blood Pressure and Arterial Hypertension – New Guidelines from a Pharmacotherapeutic Perspective

Andrej Belančić


Puni tekst: hrvatski pdf 363 Kb

str. 7-13

preuzimanja: 55

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Puni tekst: engleski pdf 363 Kb

str. 7-13

preuzimanja: 24

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Sažetak

Despite the availability of effective therapies, arterial hypertension remains a leading global health challenge. Recently published guidelines from the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC) aim to simplify and optimize hypertension treatment. These updated guidelines emphasize fixed-dose dual therapy as first-line treatment, standardize target blood pressure values to 120–129 mmHg for most patients, and highlight the role of out-of-office monitoring and non-pharmacological strategies. ESC guidelines introduce new blood pressure classifications, promote early intervention in high-risk populations, and recommend systematic screening for primary aldosteronism. Additionally, they support deprescribing in frail patients and call for objective adherence assessment. Notably, agents not traditionally classified as antihypertensives—such as GLP-1 receptor agonists and SGLT-2 inhibitors—demonstrate promising blood pressure-lowering effects and cardio-renal-metabolic benefits. This review offers a pharmacotherapeutic perspective on key updates, including initiation criteria, fourth-line treatment choices, positioning of beta-blockers, and the therapeutic potential of novel agents, advocating for a pragmatic, patient-centered approach in contemporary hypertension management.

Ključne riječi

arterial hypertension, guidelines, pharmacotherapy, fixed therapies, non-pharmacological measures

Hrčak ID:

338511

URI

https://hrcak.srce.hr/338511

Datum izdavanja:

27.10.2025.

Podaci na drugim jezicima: hrvatski

Posjeta: 133 *