Original scientific paper

Effect of Antifoams on the biosynthesis of Ergot Alkaloids by high productive Strain of Claviceps paspali F-2057

Srećko Matošić ; Hrvatska
Milena Mehak ; Hrvatska
Jagoda Šušković ; Hrvatska
Zoran Golob ; Hrvatska

Abstract

The effect of several surfactans i. e. commercial antifoams on biosynthesis of ergot alkaloids was studied. Addition of some surfactants of polyglvcole structure and Tweens to submerged cultures of high-productive strain of C. paspali F-2057 caused a change in alkaloid synthesis intensity. Pluronik (polyetoxypolypropoxy polymer) added in the range of 0.25 to 0.75% markedly stimulated the production of ergot alkaloids. The Pluronik-supplemented culture reached maximal alkaloid yields one or two days earlier than the control. Production of alkaloids increased twice. The maximal yield achieved was 5.35 gL -1 with the process productivity amounting to 17.2 mgL-1h-1.

Keywords

Hrčak ID:

160329

URI

https://hrcak.srce.hr/160329

Publication date:

31.12.1994.

Article data in other languages: croatian

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