Pregledni rad

Tumor immunotherapy side effects – early recognition and management

Ira Pavlović Ružić ; Clinic for Radiotherapy and Oncology, Clinical Hospital Center Rijeka, Rijeka, Croatia
Dag Zahirović ; Clinic for Radiotherapy and Oncology, Clinical Hospital Center Rijeka, Rijeka, Croatia
Sanja Pavlović ; Clinic for Radiotherapy and Oncology, Clinical Hospital Center Rijeka, Rijeka, Croatia
Ingrid Belac Lovasić ; Clinic for Radiotherapy and Oncology, Clinical Hospital Center Rijeka, Rijeka, Croatia

Sažetak

Implementation of immunotherapy in many cancer types has achieved positive results in tumor control and cure. The concept of immunotherapy is diff erent in comparison with conventional tumor therapies. While chemotherapy, hormonal or biological therapies target tumor cells and mechanisms, immunotherapy targets host immune system. Amplifi cation of defending possibilities or unblocking the control of the immune reactions are used. Besides positive results in tumor control, enhancing immunogenicity can provoke harm to other tissues and systems in form of adverse reactions or unwanted side effects of therapy.
Early recognition of side effects is of crucial importance and prompt care can diminish the harm and severity. Knowledge about side effects is needed, therefore good education of all medical personnel included in treatment as well as patient education must be assured prior and thorough the treatment. Writt en guidelines are provided and easy reachable and must be used.

Ključne riječi

tumor immunotherapy; side effects; management of side effects; checkpoint inhibitors; anti-CTLA-4 immunotherapy

Hrčak ID:

192224

URI

https://hrcak.srce.hr/192224

Datum izdavanja:

21.12.2017.

Podaci na drugim jezicima: hrvatski

Posjeta: 2.555 *