hrcak mascot   Srce   HID

Chemical & Biochemical Engineering Quarterly, Vol.25 No.2 June 2011.

Review article

Alcohol Dehydrogenase from Lactobacillus brevis: A Versatile Robust Catalyst for Enantioselective Transformations

S. Leuchs ; DECHEMA Karl-Winnacker-Institut, Frankfurt am Main, Germany
L. Greiner ; DECHEMA Karl-Winnacker-Institut, Frankfurt am Main, Germany; Institut für Technische und Makromolekulare Chemie, RWTH Aachen University, Aachen, Germany

Fulltext: pdf (723 KB), English, Pages 267 - 281 , downloads: 833 *

The alcohol dehydrogenase from Lactobacillus brevis (LbADH) is a versatile catalyst for enantioselective reduction of ketones. Its substrate scope is wide with high regio- and enantioselectivity. In this critical review, we have gathered the information available on the substrate scope as well as the applications reported. Quantitative information such
as productivity per catalyst, space-time yield (STY), cofactor utilisation, and stability are derived to allow comparison and assessment of practical value.

Biocatalysis; alcohol dehydrogenase; Lactobacillus brevis; critical review; application

Visits: 1.047 *