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Original scientific paper

Levels of pharmaceuticals in Slovene municipal and hospital wastewaters: a preliminary study

Anita Klančar ; Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia
Jurij Trontelj ; Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia
Albin Kristl ; Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia
Maja Zupančič Justin ; Arhel d.o.o., Ljubljana, Slovenia
Robert Roškar ; Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia

Fulltext: english, pdf (414 KB) pages 106-114 downloads: 305* cite
APA 6th Edition
Klančar, A., Trontelj, J., Kristl, A., Zupančič Justin, M. & Roškar, R. (2016). Levels of pharmaceuticals in Slovene municipal and hospital wastewaters: a preliminary study. Arhiv za higijenu rada i toksikologiju, 67 (2), 106-114. Retrieved from https://hrcak.srce.hr/159802
MLA 8th Edition
Klančar, Anita, et al. "Levels of pharmaceuticals in Slovene municipal and hospital wastewaters: a preliminary study." Arhiv za higijenu rada i toksikologiju, vol. 67, no. 2, 2016, pp. 106-114. https://hrcak.srce.hr/159802. Accessed 21 Jul. 2019.
Chicago 17th Edition
Klančar, Anita, Jurij Trontelj, Albin Kristl, Maja Zupančič Justin and Robert Roškar. "Levels of pharmaceuticals in Slovene municipal and hospital wastewaters: a preliminary study." Arhiv za higijenu rada i toksikologiju 67, no. 2 (2016): 106-114. https://hrcak.srce.hr/159802
Harvard
Klančar, A., et al. (2016). 'Levels of pharmaceuticals in Slovene municipal and hospital wastewaters: a preliminary study', Arhiv za higijenu rada i toksikologiju, 67(2), pp. 106-114. Available at: https://hrcak.srce.hr/159802 (Accessed 21 July 2019)
Vancouver
Klančar A, Trontelj J, Kristl A, Zupančič Justin M, Roškar R. Levels of pharmaceuticals in Slovene municipal and hospital wastewaters: a preliminary study. Arh Hig Rada Toksikol. [Internet]. 2016 [cited 2019 July 21];67(2):106-114. Available from: https://hrcak.srce.hr/159802
IEEE
A. Klančar, J. Trontelj, A. Kristl, M. Zupančič Justin and R. Roškar, "Levels of pharmaceuticals in Slovene municipal and hospital wastewaters: a preliminary study", Arhiv za higijenu rada i toksikologiju, vol.67, no. 2, pp. 106-114, 2016. [Online]. Available: https://hrcak.srce.hr/159802. [Accessed: 21 July 2019]

Abstracts
Pharmaceuticals in wastewater have clearly raised concern and a broad range of analytical methods has been used to assess the risk as accurately as possible. The aim of our study was to measure and compare the concentrations of atorvastatin, bisoprolol, carbamazepine, ciprofloxacin, clofibric acid, diclofenac, fluoxetine, metoprolol, and sertraline in wastewater samples taken from one municipal and one hospital wastewater treatment plant in Slovenia and to predict the potential environmental burden using the risk quotient. In both effluents only clofibric acid and fluoxetine were not detected. The measured concentrations of the remaining seven pharmaceuticals varied between the ng L-1 and the μg L-1 range. Hospital effluent showed higher concentrations, except for diclofenac and carbamazepine. However, high risk quotient was found only for ciprofloxacin and diclofenac in both municipal and hospital effluent. In conclusion, our method can provide a useful tool for systematic monitoring of pharmaceuticals commonly found in wastewater, which will enable a reliable assessment of the risks for the aquatic biota and humans. Knowing the risks will help to plan wastewater treatment and preserve our environment.

Keywords
atorvastatin; bisoprolol; carbamazepine; ciprofloxacin; clofibric acid; diclofenac, fluoxetine; hospital; LC-MS/MS; metoprolol; municipal; risk assessment; sertraline

Hrčak ID: 159802

URI
https://hrcak.srce.hr/159802

[slovenian]

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